Louisville vs. Stanford odds, picks and predictions

The no. 24 Louisville Cardinals (6-3, 4-2 ACC) meets Stanford Cardinal (2-7, 1-5) at Stanford Stadium on Saturday. Kickoff is at 3:30 p.m. ET (ACC Network). Below we look at Louisville vs. Stanford odds from BetMGM Sportsbook college football odds and make our expert college football picks and predictions.

Stanford has lost 6 straight games with their most recent loss 59-28 at the NC State Wolfpack. They failed to cover as 9.5-point underdogs while Over 46.5 hit. Stanford’s defense allowed 281 rushing yards and 5 TDs. QB Ashton Daniels was the lone bright spot rushing for 129 yards and 2 TDs on 11 carries.

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Louisville vs. Stanford odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting for a complete list of college football odds. Lines last updated Friday at 1:43 PM ET.

• Moneyline (ML): Louisville -1400 (bet $1,400 to win $100) | Stanford +825 (bet $100 to win $825)
• Against the spread (ATS): Louisville -20.5 (-110) | Stanford +20.5 (-110)
• Over/Under (O/U): 57.5 (O: -110 | U: -110)

Louisville vs. Stanford picks and predictions

Forecast

Louisville 41, Stanford 14

Moneyline

PASS.

Louisville (-1400) will win this game comfortably, so you should take your bet to the spread.

Against the spread

SAT LOUISVILLE -20.5 (-110).

Louisville enters this game off a bye week riding a 2-game winning streak, including a road win over Clemson. Meanwhile, Stanford has dropped 6 straight games, with a defense that has allowed 40+ points in 3 of its last 4 outings. The Cardinal have also failed to cover in their last home games on November 10th. Louisville has covered in 5 of its last November 6 road games against unranked teams. Stanford’s defense is allowing an average of 34.6 points per game, and with recent games, it’s hard to back them up here. Take Louisville to win on the road.

Over/Under

BET UNDER 57.5 (-110).

Louisville and Stanford trend in opposite directions for totals, with the Cardinals overshooting in 6 of 9 games and the Cardinal undershooting in 6 of 9. The line is set at 58.5, reflecting expectations for Louisville to dominate and Stanford to control the clock. Stanford has lost 2 of its last 3 games, while Louisville has gone 2-2 in its last 4. With Stanford focusing on a run-heavy offense and Louisville not needing a huge margin for the playoffs, the overflow seems unlikely. Louisville’s focus will shift to securing a bowl game instead of running up.

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