Liverpool vs Real Madrid prediction, odds, betting tips and best bets for Champions League match

After experiencing sensational form during the first few months of Arne Slott’s time in charge, Liverpool face their toughest test yet when they host defending European champions Real Madrid in the Champions League on Wednesday.

The Reds currently sit top of both the Premier League and Champions League as December approaches, an absolutely unfathomable achievement since Slot took over from the beloved Jurgen Klopp in the summer. They have won all four European games so far and have an eight-point lead at the top of the English top flight.

While Real Madrid have experienced significantly more adversity this season, sitting 18th in the Champions League table, they still provide formidable opposition. Still, Los Blancos are down a number of key players through injury, with Eder Militao and Dani Carvajal lost for the season, and both Brazilian attacking stars Vinicius Jr. and Rodrygo remained on the sidelines for the foreseeable future.

If Slot can hold serve at home, the sky is the limit for Liverpool this season on several fronts.

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Liverpool vs Real Madrid prediction, odds

• Money line lean: Liverpool (-135 at BetMGM)
• Score Prediction: Liverpool 3-1 Real Madrid

While Real Madrid prove to be a threat regardless of their form or situation, it’s just too difficult to back Los Blancos away to this kind of in-form opposition with so many injuries to work through. The Spanish giants have already struggled to push through their defensive absences and now Vinicius Jr’s injury could be too much to overcome.

Kylian Mbappe may enjoy the benefits of having the Real Madrid attack to himself, but the rest of the squad will struggle to adapt. Away at Anfield, this is too good an opportunity for Liverpool to pass up.

Liverpool vs Real Madrid match facts

• Date: Wednesday 27 November 2024
• Kickoff time: 8pm local (3pm ET / 12pm PT)
• Location: Anfield Stadium (Liverpool, England)
• Judge: Francois Letexier (FRA)
• Last meeting: Real Madrid 1-0 Liverpool (March 15, 2023 | Champions League)

Liverpool vs Real Madrid best bets

There is no one in better form in the whole of Europe than Mohamed Salah. Regardless of location, opponent or situation, the Egyptian has been able to either find the net himself or tee up a teammate for a high percentage opportunity.

Salah has either scored or assisted a goal in 13 of 16 games this season across the Premier League and Champions League, registering one of each in five of them. Given Real Madrid’s injury problems, plus Ferland Mendy’s terrible form (who Carlo Ancelotti said will get another look against Liverpool, gulp) in Salah’s side, this is a unique opportunity for the Egyptian to get his first ever win against Real Madrid on his ninth attempt.

Liverpool vs. Real Madrid betting

Plus odds for a Kylian Mbappe masterclass in a losing effort is a gift.

The French superstar has struggled to adapt to a front line that includes fellow wingers Vinicius Jr. and Rodrygo. Now, with both Brazilian teammates sidelined through injury, the attack will lean heavily on Mbappe, a situation in which he thrives.

With a goal from five tries against Leganes at the weekend, Mbappe is now potentially finding his footing in Madrid and his influence will be key if the Spanish visitors are to have any attacking joy against an in-form Liverpool backline. He is familiar with such a result having scored in a 3-2 defeat at Anfield to PSG way back in 2018.