Christina Applegate Shares How ‘I Lay in Bed Screaming’ from MS Pain

Christina Applegate shared a raw look at the physical side of multiple sclerosis, talking about how the disease can often make her “scream” in pain.

“I was lying in bed screaming – like the sharp pain, the pain, the squeeze,” Death to me actress said, revealing that her symptoms have developed during the Nov. 5 episode of Messythe podcast she co-hosts with Jamie-Lynn Sigler, who also has MS.

On the episode, the twosome spoke with Rory Kandel, the owner of Rory’s Bakerywho shared that her MS also “manifests itself as pain.”

“It feels like I have knives in my stomach,” Kandel said. “Like, I’ll be laying in bed and I’ll wake up and I physically can’t turn from side to side.”

“It’s the worst,” said Applegate, who was diagnosed with multiple sclerosis in 2021. Cleveland Clinic explains that the progressive disease “damages the protective covering around nerves called myelin in your central nervous system. This can cause muscle weakness, vision changes, numbness and memory problems.”

“Do you feel it?” Kandel asked, prompting Applegate to reply, “Every single day of my life.”

“I can’t even pick up my phone sometimes because now it’s raised in my hands, so I’ll try to get my phone or get my remote to turn on the TV, or sometimes I can’t even hold them. I can’t open bottles now.”

“But we look good,” Kandel said.

“Because that’s the beauty of the invisible disease,” Applegate said.

The Married…with children alum shared that depending on her pain levels, “I would just lay in bed the whole time. I mean, I worked for almost 50 years, so I’m kind of okay with it.”

Getting out of bed in the morning can be so painful that Applegate compared it to “the floor is lava. The floor is lava.”

“Looks like someone put a hot fire poker up my hole,” Sigler said of the day’s first step.

“I put my feet on the ground and they hurt extraordinarily to the touch,” Applegate said. “I was like, yeah. Gotta go back to my bed and pee in my diaper because I don’t want to go all the way to the damn bathroom,” she said, quickly adding, “I’m not actually laying here peeing in my bed diaper . It’s just a joke.”

“But it’s like it’s so freaking painful and so hard and so awkward.”

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