49ers QB Brock Purdy, DE Nick Bosa out for Week 12 game vs. Packers

San Francisco 49ers quarterback Brock Purdy is out for Week 12’s matchup with the Green Bay Packers. Defensive end Nick Bosa also will not play.

Purdy did not practice Friday, making his status uncertain. But head coach Kyle Shanahan officially announced he was out when he met with reporters after practice. Brandon Allen starts at quarterback against Green Bay.

Additionally, left tackle Trent Williams is listed as questionable with an ankle injury and will be a game-time decision, according to Shanahan.

Earlier Friday d. The NFL listed Purdy as out on his injury report. He was previously listed as questionable, but is now officially downgraded.

Bosa was also listed as out on the injury report due to hip and oblique issues. He suffered the injury in practice on Nov. 6 and played through the injury in Week 10’s matchup with Tampa Bay.

He left last week’s matchup with the Seahawks in the third quarter and did not return. After the game, Bosa told reporters that he hurt his oblique at the same time as compensating for the hip injury.

Right shoulder soreness limited Purdy in practice Wednesday and Thursday, and he did not participate in the team’s final practice session before traveling to Green Bay.

General manager John Lynch told KNBR Friday that Purdy had an MRI and described his status for Sunday as “weak.”

“Hopefully he makes progress and we can have a shot this weekend, but we’ll see,” Lynch said. “I think it’s flimsy.”

At Thursday’s practice, Purdy’s participation consisted of soft throws while San Francisco’s three other quarterbacks went through drills with QB coach Brian Griese. Purdy stopped after about five minutes, had his shoulder worked on by trainers and went back to the locker room, according to reporters at the scene.

Purdy appeared to suffer the injury during last week’s 20-17 loss to the Seattle Seahawks. He finished the game but did not make any throws over 10 yards after the hit that potentially hurt him. There was no indication afterward that Purdy was injured.