NBA Odds, Picks, Best Bets Wednesday

On Wednesday, the Memphis Grizzlies will host the Philadelphia 76ers on the second night of a home back-to-back.

Just like last year, Memphis has already struggled with many injuries, with Ja Morant, Desmond Bane, Marcus Smart, GG Jackson, Vince Williams Jr. and Luke Kennard all missing some time.

Now, Zach Edey will be out after spraining his ankle Sunday night, and Williams will also be out after suffering an ankle injury Tuesday night.

Despite another injury-riddled start to the season, the Grizzlies have found a way to float above .500. Can they continue to do so against a roaring Sixers team?

76ers vs. Grizzlies odds

Team Spread Moneyline Total
76ers -2.5 (-110) -140 o219.5 (-110)
Grizzlies +2.5 (+110) +120 u219.5 (-110)
Odds via bet365

76ers vs. Grizzlies’ prediction

If you predicted the 76ers would start the season with a 2-11 record despite signing Paul George, you’re either crazy or had Biff’s almanac from “Back to the Future 2.”

The Sixers are in free fall. They have lost nine of their last 10 games and are tied with Washington for the worst record in the Eastern Conference and the NBA.

So far in the 2024-2025 campaign, the Sixers have the third-worst net rating and lowest effective field goal percentage in the NBA.

In addition, former MVP Joel Embiid has only been available for three of the team’s games.

Even when available, Embiid has been a shell of himself, averaging just 14.7 points and 6.3 rebounds per game.

Conversely, despite struggling to keep their players healthy, the Grizzlies have found some success, except for Tuesday night.

After an embarrassing home loss to the Nets on Oct. 30, Memphis had reeled off four straight double-digit home wins before Tuesday’s loss to Denver.

In that four-game stretch, Memphis had the second-highest net rating (+18.5) and highest rebounding percentage. It also ranked first in points in the paint and second in opponent second-chance points.


Jaren Jackson Jr. is one of the few healthy Grizzlies.
Jaren Jackson Jr. is one of the few healthy Grizzlies. Getty Images

76ers vs. Grizzlies’ pick

I can’t believe I’m saying this, but this could be a good bounce-back spot for the Sixers despite their rough start.

Philly may return Maxey to the lineup, uniting him, Embiid and George for the first time all season.

Memphis will be on the second night of a back-to-back and likely won’t have Edey to defend Embiid, meaning Brandon Clarke (6-foot-8) will have to step into the role if head coach Taylor Jenkins stick to the small. -ball formations.

Further, Memphis has been hit or miss on the offensive end of the floor, and its trouble developing cohesion could be tied to the various injuries it has already dealt with.


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Unfortunately, things have gotten stickier since losing Williams again.

We’ll have to wait and see if Maxey is available, but if he plays, the Sixers can leave Memphis with a win.

THE PICK: 76ers -3 (-105, BetRivers)* Assuming Tyrese Maxey plays


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Andrew Norton disabled NBA, WNBA, NFL, college basketball and football, UFC and golf. During the 2022-23 NBA season, he posted an outstanding ROI of 14.1%, cashed in 60% of his NBA spread picks and led Tallysight in its SportsIQ metric.